Канал: DennisLal

Situps4seizures - Epilepsy Awareness - Lal Research Group

Situps4seizures - Epilepsy Awareness - Lal Research Group

Data-driven modeling of Alzheimer's disease progression

Data-driven modeling of Alzheimer's disease progression

Dravet Syndrome - When the experiment is on your child

Dravet Syndrome - When the experiment is on your child

Deep learning of EEG spectrograms for prognosis in REM behavior disorder

Deep learning of EEG spectrograms for prognosis in REM behavior disorder

Intro to meta-analysis of GWASs

Intro to meta-analysis of GWASs

Inferring IBD of sample ancestors promotes high resolution relative detection

Inferring IBD of sample ancestors promotes high resolution relative detection

The genetic landscape in the US

The genetic landscape in the US

Identifying repeat expansions in short read sequencing: Compassion of tools

Identifying repeat expansions in short read sequencing: Compassion of tools

Hail 0.2: A framework for scalable genetic data analysis in Python

Hail 0.2: A framework for scalable genetic data analysis in Python

Python coding tutorial 4 - Scikit-learn: A machine learning library for python

Python coding tutorial 4 - Scikit-learn: A machine learning library for python

Phenotypic spectrum of patients with SLC6A1 mutations

Phenotypic spectrum of patients with SLC6A1 mutations

Python coding tutorial 3 - Data Manipulation w. Numpy and Pandas

Python coding tutorial 3 - Data Manipulation w. Numpy and Pandas

Data-driven approaches improve Tau-PET biomarkers in Alzheimer's disease

Data-driven approaches improve Tau-PET biomarkers in Alzheimer's disease

Python Programming Basics Tutorial 2

Python Programming Basics Tutorial 2

Moment-matching Methods for heritability and co-heritability analysis

Moment-matching Methods for heritability and co-heritability analysis

Phenotypic convergence in the brain - Transcription factors & neuronal characters

Phenotypic convergence in the brain - Transcription factors & neuronal characters

Python Programming Basics Tutorial 1

Python Programming Basics Tutorial 1

Efficient pedigree recording for fast population genetics simulation

Efficient pedigree recording for fast population genetics simulation

Modeling Peptide Recognition Domains in Protein Sequences at Scale

Modeling Peptide Recognition Domains in Protein Sequences at Scale

From a fixed ggplot2 figure to an interactive Shiny App

From a fixed ggplot2 figure to an interactive Shiny App

One family's journey to an SLC13A5 Deficiency diagnosis

One family's journey to an SLC13A5 Deficiency diagnosis

Life with a child suffering from a rare genetic disease - SCN2A

Life with a child suffering from a rare genetic disease - SCN2A

GWAS of 1 million people identifies 111 loci for atrial fibrillation

GWAS of 1 million people identifies 111 loci for atrial fibrillation

10 quick tips for machine learning in computational biology

10 quick tips for machine learning in computational biology

Somatic mTOR Pathway mutation & Continuum of Cortical Dysplasias

Somatic mTOR Pathway mutation & Continuum of Cortical Dysplasias

ScRNA-seq characterization of 20 organs & tissues from mouse

ScRNA-seq characterization of 20 organs & tissues from mouse

The effect of education on adult mortality, health, and income

The effect of education on adult mortality, health, and income

Tutorial: Fast QC & generation of summery statistics of ClinVar data

Tutorial: Fast QC & generation of summery statistics of ClinVar data

Multiscale rhythms of interictal epileptiform activity modulate seizure risk

Multiscale rhythms of interictal epileptiform activity modulate seizure risk

GWAS implicates CHRNA2 in cannabis use disorder

GWAS implicates CHRNA2 in cannabis use disorder

Google BigQuery for working with very large genetic and phenotype data

Google BigQuery for working with very large genetic and phenotype data

The largest de novo var. study of Neurodevelopmental Disorders w. Epilepsy

The largest de novo var. study of Neurodevelopmental Disorders w. Epilepsy

Introduction/tutorial to visual programming in Orange (python-based) a Data Mining Tool

Introduction/tutorial to visual programming in Orange (python-based) a Data Mining Tool

Early Life Epileptic Encephalopathies: A Personal and Scientific Persepctive

Early Life Epileptic Encephalopathies: A Personal and Scientific Persepctive

Unexpectedly Complex Architecture for Skin Pigmentation in Africans

Unexpectedly Complex Architecture for Skin Pigmentation in Africans

SCN2A - what's new in 2017

SCN2A - what's new in 2017

X chromosome rare reg. var. associated with high risk for type 2 diabetes

X chromosome rare reg. var. associated with high risk for type 2 diabetes

A Loss-Of-Function Splice Acceptor Variant in IGF2 is Protective for Type 2 Diabetes

A Loss-Of-Function Splice Acceptor Variant in IGF2 is Protective for Type 2 Diabetes

Population variability of intron size & gene expression variability

Population variability of intron size & gene expression variability

Educational attainment GWAS results to aid identifying genetic heterogeneity of schizophrenia

Educational attainment GWAS results to aid identifying genetic heterogeneity of schizophrenia

130k families & shared genetic and environmental determinants

130k families & shared genetic and environmental determinants

Genome sequencing & analysis of fetal genomes from amniotic fluid

Genome sequencing & analysis of fetal genomes from amniotic fluid

Single-cell methylomes & neuronal subtypes in mammalian cortex

Single-cell methylomes & neuronal subtypes in mammalian cortex

Postsynaptic interactome profiles & Complex brain disorders

Postsynaptic interactome profiles & Complex brain disorders

Functional consequences of intelligence GWAS loci from 87,740 individuals

Functional consequences of intelligence GWAS loci from 87,740 individuals

Novel transcripts in DLG2 linked to developmental disorders & ID

Novel transcripts in DLG2 linked to developmental disorders & ID

Large-scale cognitive GWAS & tissue-specific expression & nootropic drug targets

Large-scale cognitive GWAS & tissue-specific expression & nootropic drug targets

Increased ventricular volumes in psychosis - GWAS findings from the B-SNIP deep phenotyping study

Increased ventricular volumes in psychosis - GWAS findings from the B-SNIP deep phenotyping study

Medical relevance of protein-truncating variants across 337,208 individuals in the UK Biobank study

Medical relevance of protein-truncating variants across 337,208 individuals in the UK Biobank study

Global Biobank Engine - Manuel Rivas

Global Biobank Engine - Manuel Rivas

Basics of SCN2A disorders - Dennis Lal

Basics of SCN2A disorders - Dennis Lal

Life lost & life expectancy in schizophrenia

Life lost & life expectancy in schizophrenia

Using Gene families for variant interpretation & identification of novel disease-associated genes

Using Gene families for variant interpretation & identification of novel disease-associated genes

Regional missense constraint improves variant deleteriousness prediction

Regional missense constraint improves variant deleteriousness prediction

Genetics of sex bias in the prevalence of ADHD

Genetics of sex bias in the prevalence of ADHD

Non-genetic allelic effects in the Mammalian brain

Non-genetic allelic effects in the Mammalian brain

Impact of rare coding variants across the phenotypic spectrum in 100K individuals

Impact of rare coding variants across the phenotypic spectrum in 100K individuals

Discovery Of The First Genetic Risk Factors For ADHD

Discovery Of The First Genetic Risk Factors For ADHD

Population-specific gene expression imputation to improve prediction of pharmacogenomic traits

Population-specific gene expression imputation to improve prediction of pharmacogenomic traits

Genetic variants regulating expression levels and isoform diversity during embryogenesis

Genetic variants regulating expression levels and isoform diversity during embryogenesis

Promoter shape varies across populations and affects promoter evolution and expression noise

Promoter shape varies across populations and affects promoter evolution and expression noise

GWAS of cognitive empathy: heritability & cor. with psy. conditions/traits & brain volumes.

GWAS of cognitive empathy: heritability & cor. with psy. conditions/traits & brain volumes.

SORVA - a tool calculating the statistical significance of rare disease associated variants

SORVA - a tool calculating the statistical significance of rare disease associated variants

Nicotine reverses hypofrontality in animal models of addiction & schizophrenia

Nicotine reverses hypofrontality in animal models of addiction & schizophrenia

Pleiotropic Genetic Effects Influencing Sleep and Neurological Disorders

Pleiotropic Genetic Effects Influencing Sleep and Neurological Disorders

Genetic similarity among friends and schoolmates

Genetic similarity among friends and schoolmates

Sudden Unexpected Death in Epilepsy: Epidemiology, Mechanisms & Prevention

Sudden Unexpected Death in Epilepsy: Epidemiology, Mechanisms & Prevention

Molecular Diversity of Midbrain Development in Mouse, Human, and Stem Cells

Molecular Diversity of Midbrain Development in Mouse, Human, and Stem Cells

Disease heritability from 4.7M familial relationships inferred from electronic health records

Disease heritability from 4.7M familial relationships inferred from electronic health records

De novo mutations in regulatory elements cause neurodevelopmental disorders

De novo mutations in regulatory elements cause neurodevelopmental disorders

Staying on top of the research literature with little effort - Dennis Lal

Staying on top of the research literature with little effort - Dennis Lal

Rare Variant, Gene-Based Association Study Of Hereditary Melanoma Using Whole Exome Sequencing

Rare Variant, Gene-Based Association Study Of Hereditary Melanoma Using Whole Exome Sequencing

Seminar: How protein structures can help understanding missense variation - Jakob Jespersen

Seminar: How protein structures can help understanding missense variation - Jakob Jespersen

Role of de novo genetic variants in neurodevelopmental disorders - Jack Kosmicki

Role of de novo genetic variants in neurodevelopmental disorders - Jack Kosmicki

Common genetic variants in families with autism. New method & application.

Common genetic variants in families with autism. New method & application.

Using PPI networks to catalyze genomic variant interpretation - Taibo Li

Using PPI networks to catalyze genomic variant interpretation - Taibo Li

Genetic risk prediction across diverse human populations - Alicia Martin

Genetic risk prediction across diverse human populations - Alicia Martin

Virtual Cortical Resection and Prediction of Seizure Network Control

Virtual Cortical Resection and Prediction of Seizure Network Control

Formation of new chromatin domains (neo-TADs) determines pathogenicity of genomic duplications

Formation of new chromatin domains (neo-TADs) determines pathogenicity of genomic duplications

Psychiatric disorders and phenotypes for non-clinical scientists

Psychiatric disorders and phenotypes for non-clinical scientists

Ultra-rare genetic variation in common epilepsies - Slave Petrovski

Ultra-rare genetic variation in common epilepsies - Slave Petrovski

Histone Acetylome-wide Association Study of Autism

Histone Acetylome-wide Association Study of Autism

Gene expression + summary statistics = identify genes for 30 complex traits

Gene expression + summary statistics = identify genes for 30 complex traits

The human functional genome defined by genetic diversity -Julia di Iulio

The human functional genome defined by genetic diversity -Julia di Iulio

Disease associated rare Copy Number Variants in Schizophrenia - Daniel Howrigan

Disease associated rare Copy Number Variants in Schizophrenia - Daniel Howrigan

Hail: Exploring and analyzing very large genetic data - Jon Bloom

Hail: Exploring and analyzing very large genetic data - Jon Bloom

Imputing transcriptome for gene association analyses - Costin Leu

Imputing transcriptome for gene association analyses - Costin Leu

Genetics of ALS and frontotemporal dementia - Sali Farhan

Genetics of ALS and frontotemporal dementia - Sali Farhan

The genetic architecture of type 2 diabetes - Henrike Heine

The genetic architecture of type 2 diabetes - Henrike Heine

De novo genetic variants in developmental disorders - Jeremy McRae

De novo genetic variants in developmental disorders - Jeremy McRae

Mosaic Mutations in Blood Associated with Solid Tumors Cancers - Nikita Artomov

Mosaic Mutations in Blood Associated with Solid Tumors Cancers - Nikita Artomov

Contribution of Microdeletions in Common Generalized and Focal epilepsies - Eduardo Perez

Contribution of Microdeletions in Common Generalized and Focal epilepsies - Eduardo Perez

Rare variants in patients with Schizophrenia - Giulio Genovese

Rare variants in patients with Schizophrenia - Giulio Genovese

An introduction to rare variant testing in common disorders - Manuel Rivas

An introduction to rare variant testing in common disorders - Manuel Rivas

Rare variants affecting educational attainment - Andrea Ganna

Rare variants affecting educational attainment - Andrea Ganna

Rare variants in patients with Autism - Jack Kosmicki

Rare variants in patients with Autism - Jack Kosmicki

The importance of common variants in neurodevelopmental disorders - Verneri Anttila

The importance of common variants in neurodevelopmental disorders - Verneri Anttila