Канал: Margaret's Molecular Models

Stereochemical Specificity of Enzymes

Stereochemical Specificity of Enzymes

Absolute Specificity of Enzymes

Absolute Specificity of Enzymes

Building a Substrate Model

Building a Substrate Model

Building a Protein Model

Building a Protein Model

Folding Protein to Create Active Site

Folding Protein to Create Active Site

Impact of Substrate Bond Rotation on Binding

Impact of Substrate Bond Rotation on Binding

Impact of Mutation on Substrate Binding

Impact of Mutation on Substrate Binding

Presumptive substrate doesn't fit correctly in enzyme active site.

Presumptive substrate doesn't fit correctly in enzyme active site.

Flipping Model Pieces to Explore Enzyme Inhibition

Flipping Model Pieces to Explore Enzyme Inhibition

Competitive Enzyme Inhibition

Competitive Enzyme Inhibition

Noncompetitive (Allosteric) Enzyme Inhibition

Noncompetitive (Allosteric) Enzyme Inhibition

Catabolic Reaction

Catabolic Reaction

Anabolic Reaction

Anabolic Reaction

Comparison of chemical properties of two presumptive substrates

Comparison of chemical properties of two presumptive substrates

Substrate fits in active site pocket based on shape and chemical properties

Substrate fits in active site pocket based on shape and chemical properties

Adding amino acids to the protein backbone

Adding amino acids to the protein backbone

Clip colors represent chemical properties of each amino acid sidechain.

Clip colors represent chemical properties of each amino acid sidechain.

Cysteine residues can form a covalent bond, called a disulfide (S-S) bond.

Cysteine residues can form a covalent bond, called a disulfide (S-S) bond.

Acidic and basic residues interact on the surface of proteins, forming salt bridges.

Acidic and basic residues interact on the surface of proteins, forming salt bridges.

Polar residues face outward, where they interact with the watery environment of the cell.

Polar residues face outward, where they interact with the watery environment of the cell.

Hydrophobic sidechains point inside the protein.

Hydrophobic sidechains point inside the protein.

Adding amino acids to the protein backbone

Adding amino acids to the protein backbone

All proteins are synthesized with methionine at the N terminus.

All proteins are synthesized with methionine at the N terminus.

Identifying Amino Acid Sidechains and Sorting Them Based on Their Chemical Properties

Identifying Amino Acid Sidechains and Sorting Them Based on Their Chemical Properties

Orienting Beta Strands to Create Parallel Beta Sheet

Orienting Beta Strands to Create Parallel Beta Sheet

Alpha Helix Backbone and Backbone with Sidechains

Alpha Helix Backbone and Backbone with Sidechains

Beta Sheet Backbone and Beta Sheet with Sidechains

Beta Sheet Backbone and Beta Sheet with Sidechains

Addition of Sidechains to Parallel Beta Sheet

Addition of Sidechains to Parallel Beta Sheet

Adding Hydrogen Bonds to Parallel Beta Sheet

Adding Hydrogen Bonds to Parallel Beta Sheet

Adding Sidechains to Antiparallel Beta Sheet

Adding Sidechains to Antiparallel Beta Sheet

Adding Hydrogen Bonds to Antiparallel Beta Sheet

Adding Hydrogen Bonds to Antiparallel Beta Sheet

Orienting Beta Strands to Create Antiparallel Beta Sheet

Orienting Beta Strands to Create Antiparallel Beta Sheet

Constructing a Beta Sheet

Constructing a Beta Sheet

Adding Sidechains to Alpha Helix Backbone

Adding Sidechains to Alpha Helix Backbone

Adding Hydrogen Bonds to Alpha Helix Backbone

Adding Hydrogen Bonds to Alpha Helix Backbone

Constructing an Alpha Helix Backbone

Constructing an Alpha Helix Backbone

Alpha Helix and Beta Sheet Backbone Pieces

Alpha Helix and Beta Sheet Backbone Pieces

Translation 7

Translation 7

Translation 6

Translation 6

Translation 5

Translation 5

Translation 4

Translation 4

Translation 3

Translation 3

Translation 2

Translation 2

Translation 1

Translation 1

Transcription 5

Transcription 5

Transcription 4

Transcription 4

Transcription 3

Transcription 3

Transcription 2

Transcription 2

Transcription 1

Transcription 1

DNA Replication 9

DNA Replication 9

DNA Replication 8

DNA Replication 8

DNA Replication 7

DNA Replication 7

DNA Replication 6

DNA Replication 6

DNA Replication 5

DNA Replication 5

DNA Replication 4

DNA Replication 4

DNA Replication 3

DNA Replication 3

DNA Replication 2

DNA Replication 2

DNA Replication 1

DNA Replication 1

Molecules of Life: Protein - aquaporin

Molecules of Life: Protein - aquaporin

Molecules of Life: DNA

Molecules of Life: DNA

Molecules of Life:Plasma Membrane and Aquaporin

Molecules of Life:Plasma Membrane and Aquaporin

Molecules of Life: Carbohydrates - cellulose

Molecules of Life: Carbohydrates - cellulose

Molecules of Life: Carbohydrates - glycogen

Molecules of Life: Carbohydrates - glycogen

Molecules of Life: Carbohydrates - Starch

Molecules of Life: Carbohydrates - Starch

Molecules of Life: Phospholipid bilayer (membrane)

Molecules of Life: Phospholipid bilayer (membrane)

Molecules of Life: Water

Molecules of Life: Water

Water: interaction with sodium chloride

Water: interaction with sodium chloride

Water: interactions with polar ethanol

Water: interactions with polar ethanol

Water: interactions with ethane.

Water: interactions with ethane.

Water: oxygen-hydrogen interactions

Water: oxygen-hydrogen interactions

Water: hydrogen - hydrogen interactions

Water: hydrogen - hydrogen interactions

Water: oxygen-oxygen interactions

Water: oxygen-oxygen interactions

Water: structure

Water: structure