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Asthma and chronic obstructive pulmonary disease (COPD) are chronic lung diseases marked by an inflammation and narrowing of the airways. This pharmacology lecture discusses the basic pathophysiology of asthma and COPD as well as mechanism of action of various drugs used in treatment of these diseases. Drugs mentioned include: β2 adrenergic agonists - Albuterol, Levalbuterol, Arformoterol, Formoterol, Vilanterol, and Salmeterol; Muscarinic antagonists (anticholinergics) - Ipratropium, Tiotropium, Aclidinium and Umeclidinium; Leukotriene modifiers - Montelukast, Zafirlukast, and Zileuton; Phosphodisterase inhibitors - Theophylline and Roflumilast; Anti-IgE monoclonal antibody - Omalizumab; Antihistamines; Corticosteroids - Beclomethasone, Budesonide, Ciclesonide, Fluticasone, Mometasone, Triamcinolone, Dexamethasone, Methylprednisolone, Prednisone, and Prednisolone.

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00:00 Intro
00:24 Asthma pathophysiology
03:43 COPD pathophysiology
04:58 β2 adrenergic agonists
06:06 Muscarinic antagonists
07:09 Leukotriene modifiers
07:58 Phosphodisterase inhibitors
09:07 Anti-IgE antibody & Antihistamines
10:02 Corticosteroids

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