Rudolf Stadler, MD, PhD, University Medical Center Minden, Minden, Germany, gives an update on the Phase II PARCT trial (NCT03357224) investigating the PD-L1 inhibitor atezolizumab for the treatment of stage IIb-IV mycosis fungoides or Sézary syndrome, for patients who become relapsed/refractory (R/R) after a previous systemic treatment. Prof. Stadler discussess challenges around the safety profile of atezolizumab and the need to find biomarkers which enable the identification of patients who would benefit the most from this therapy. This interview took place at the EORTC Cutaneous Lymphoma Group 20-21 meeting in Marseille.
PARCT: atezolizumab for CTCL and next steps
Теги
Speaker: Rudolf StadlerInstitution: University Medical Center MindenEvent: EORTC CLTF 2021Format: InterviewSubject: Cutaneous T-Cell LymphomaSubject: LymphomaSubject: Non-Hodgkin LymphomaSezary syndromemycoisis fungoidesPD-L1Medicines: AtezolizumabMedicines: AntibodiesField: TreatmentField: Immuno-OncologyField: Trial UpdatesrelapsedrefractoryR/Rsystemic treatmentNCT03357224Trial: PARCTbiomarkerssafetyimmune checkpoint inhibitors