Enrique Grande, MD, MD Anderson Cancer Center Madrid, Madrid, Spain, comments on the future of antibody-drug conjugates (ADCs) for the management of urothelial carcinoma. Enfortumab vedotin has demonstrated very encouraging efficacy in clinical trials and the TROPiCS-04 trial (NCT04527991) will additionally investigate sacituzumab govitecan, a Trop2 directed ADC, in bladder cancer. Novel ADCs also include disitamab vedotin, which will be assessed against avelumab. This interview took place at the ASCO GU Cancers Symposium 2024 in San Francisco, CA.
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