Patients with coronary artery disease are at risk for neuropsychological decline. Postoperative increases in neurofilament light concentration in blood, a marker of neuronal injury, have been associated with delirium after noncardiac surgery.
In an observational study of 167 cardiac surgery patients nested within a randomized controlled study of blood pressure management, higher baseline neurofilament light concentration in blood is associated with worse baseline cognition, but improvement in cognition at 1 year. An increase in neurofilament light on postoperative day 1 is associated with a greater decline in cognition at 1 year.
Read the Research
[ Ссылка ]
Stay Engaged with ANESTHESIOLOGY
[ Ссылка ]
[ Ссылка ]
[ Ссылка ]
#anesthesiology #anesthesiologist #medicalresearch #cardiacsurgery
