Mitochondria, known as the cell's "powerhouses," generate ATP, the primary cellular energy source. Dysfunction leads to reduced energy production, affecting cell and tissue function, implicated in various health conditions. Dysfunctional mitochondria contribute to oxidative stress, damaging cells and triggering inflammation. Addressing mitochondrial dysfunction is crucial for cellular health and preventing health issues. Heavy metals, pesticides, infections, and certain drugs can cause dysfunction through oxidative stress, disrupting cellular processes and compromising energy production. Metals like lead, mercury, and cadmium interfere with electron transport, generating ROS and damaging mitochondrial DNA. Pesticides disrupt mitochondrial membranes and enzyme activities, while infections impact function through direct damage or inflammatory responses.

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