Serguei Tchessalov, PhD, Research Fellow at Pfizer, Lyophilization SME - Pfizer Inc.
The webinar "Evaluation of Alternative Drying Technologies to Vial Lyophilization" will cover the maturity state of various drying technologies, including foam drying, spray freeze-drying, and spin freeze-drying. The presentation will discuss the advantages and disadvantages of foam drying, such as improved storage stability of pharmaceutical products at increased temperatures, faster drying cycles, and better preservation of biologic activity. It will also compare conventional vial freeze-drying with spray freeze-drying in terms of freezing time, drying time, reconstitution time, accuracy of fill, aseptic nature, flexibility in dose, and potential benefits. The webinar will provide insights into the development of reliable models for spray-freezing and rotary drying, as well as the potential applications and pros and cons of spin freeze-drying. Additionally, it will present the results of studies on lipid nanoparticles, adeno-associated virus, and protein, highlighting the impact of different drying technologies on product attributes. The presentation will also address the maturity state of single and multi-vial lab scale units and pilot scale in development for spin freeze-drying. Overall, the webinar will offer a comprehensive overview of the advancements and challenges in alternative drying technologies, providing valuable insights for professionals in the pharmaceutical industry.
