This video describes the differences in calibration processes for analog pH sensors and digital pH sensors for the pharmaceutical industry. The video highlights the process and compliance improvements that pharmaceutical manufacturers can achieve with digital pH sensors using Intelligent Sensor Management (ISM) technology over traditional analog sensors.
For more on Good Operating Procedures for pH sensors in the pharmaceutical industry:
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For compliance and record keeping, digital ISM pH sensors can be calibrated directly at your computer via a USB connection, eliminating the need for manual record keeping which can be subject to human error. A PDF document can then be generated with all of the calibration data if required.
Additionally, it allows you to calibrate in the comfort of a lab, instead of directly at the process transmitter. Because calibration data on an ISM pH sensor is stored in the sensor itself, the pH sensor can be calibrated away from the process, and then you can simply bring it back to the process to "plug and measure".
After a batch or fermentation process, digital ISM pH sensors can be connected directly to iSense software to capture all relevant process data, including exposure to SIP cycles and maximum temperature during the process.
Digital ISM technology offers additional benefits for pH sensors besides those highlighted in this video, including the Dynamic Lifetime Indicator, Adaptive Calibration Timer and Time To Maintenance predictive maintenance tools. These features use your process conditions and a proprietary algorithm to help reduce any unplanned downtime, and ensure that your pH electrode does not fail during a batch process.
METTLER TOLEDO offers a wide range of pH sensors for different applications within the pharmaceutical industry including measurement during fermentation, measurement during chemical reactions, measurement during separation and measurement of regulated waters.
0:00 Introduction
0:11 Analog pH sensor calibration
0:57 Digital pH sensor calibration
1:34 Analog pH sensor installation and measurement
1:54 Digital pH sensor installation and measurement
2:22 Benefits of digital ISM
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