In this video I have briefly explained a diseases related to pentose phosphate pathway (which is also referred as hexose monophosphate shunt). This disease in question is glucose 6-phosphate dehydrogenase deficiency (G6PD deficiency) which causes hemolytic anemia due to deficiency of NADPH. NADPH deficiency leads to decreased GSH (reduced glutathione) which leads to increased presence of reactive oxygen species (ROS).

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Key words:
Glucose 6-phosphate
G6PD deficiency
species
ribose 5 phosphate
NADPH
GSH
glutathione
GSSG
ROS
Heinz bodies
hemolytic anemia
Beutler florescence
bite cells
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