Glycopeptides are group of antibiotics that work on the bacterial cell wall (cell wall inhibitors) and in this video I will talk about the pharmacokinetics, mechanism of action, antibacterial spectrum, therapeutic Uses and adverse effects …
- Vancomycin is the prototype drug of the glycopeptides but there is others like the Teicoplanin…
- Vancomycin have significantly higher molecular weight than penicillin, and it is taken intravenously mostly but sometimes taken orally for specifically to treat the pseudomembranous colitis caused by Clostridium difficile, it can’t cross the blood brain barrier…
- Vancomycin is active on the cell wall of the gram positive bacteria (it doesn’t work on gram negatives), it binds into the glycan units and preventing them from linking together…
- Vancomycin is active against MRSA, MRSE, C difficile, enterococcus facium and facials …
- Vancomycin is never the first choice to treat infections, it is usually second or third and it never given alone, it should be combined with other antibiotics like aminoglycosides and cephalosporins…
-------------------------------------------------------------------------------------------------
* Support this work via Patreon: [ Ссылка ]
** More amazing antibiotic videos in my Antibiotics Pharmacology Series: [ Ссылка ]
*** Subscribe for more Pharmacology content: www.youtube.com/c/mustafasalahalden?sub_confirmation=1
**Thumbnail picture credit: MorgueFile : see [1], CC BY-SA 3.0 [ Ссылка ], via Wikimedia Commons
Video Timestamps
0:00 Introduction
1:05 Pharmacokinetics
3:40 Mechanism of Action
5:10 Antibacterial Spectrum
6:33 Therapeutic Uses
9:01 Adverse effects
