Mark Levis, MD, PhD, Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, discusses the APL0406 clinical trial (NCT00482833) that led to the approval of arsenic trioxide (ATO) and all-trans retinoic acid (ATRA) without chemotherapy for the treatment of acute promyelocytic leukemia (APL). This trial demonstrated that patients treated only with ATO+ATRA experienced long-term survival rates between 95-100%. This interview took place at the 2021 Relapse After HSCT² Workshop in New York, NY.
The efficacy of ATO and ATRA for APL
Теги
Speaker: Mark LevisInstitution: Johns Hopkins Sidney Kimmel Comprehensive Cancer CenterEvent: Relapse After HSCT 2021Format: InterviewSubject: Acute Promyelocytic LeukemiaSubject: LeukemiaTrial: APL0406Field: TreatmentField: Trial UpdatesMedicines: All-trans Retinoic AcidMedicines: Arsenic TrioxideAPMLATOall-trans retinoic acid (ATRA)chemotherapyNCT00482833long-term survival rate