This comprehensive video offers an in-depth exploration of de novo protein design using cutting-edge tools like RFDiffusion, ProteinMPNN, AlphaFold, and additional scoring and filtering techniques that streamline the workflow. We provide a thorough overview of how a de novo protein design project can be executed from start to finish with Levitate Bio's software, delving into the science behind our most advanced tools, RFDiffusion and ProteinMPNN. Through a detailed demonstration of a real-world design project, we illustrate the practical application of these tools. Finally, we share additional insights about Levitate Bio and how our expertise can support your protein design goals.
CONTENT
0:00 - Opening Remarks
0:52 - Introduction
1:29 - De Novo Design Workflow
7:52 - Scientific Background
14:04 - Demonstration of a De Novo Design
35:43 - Information about Levitate Bio
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