Animation sequence revealing the pathway of cancer cells as they leave the primary breast cancer tumor and gain access to the rest of the body via the lymphatic system. The lymphatic system plays an instrumental role in the metastasis, or spread, of breast cancer.

Opener for series that discusses ongoing research to identify a growing number of promising therapies for triple-negative breast cancer (TNBC), including a chemotherapy-plus-immunotherapy combination. Promising therapies such as therapeutic agents and antibody drug conjugates are also being developed to prolong life and improve quality.

Triple-negative breast cancer (TNBC) is named as such because it lacks the expression of progesterone receptors, estrogen receptors, and HER2/neu.

While other breast cancer types have seen improved survival rates, TNBC remains difficult to treat due to its complex nature. It is an aggressive subtype and comprises about 15% of all breast cancers.

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