Welcome to another informative episode of the Wellness Zone Podcast with Dr. Barry Sears and Mary Perry! This week, we're diving into the fascinating history of “Wonder Drugs”—dating back a whopping 3,500 years! But what exactly is a wonder drug? Think of it as the superheroes of medicine, tackling the toughest health problems of their time. From ancient willow bark to modern aspirin, all the way to today’s GLP-1, we'll explore how these mighty remedies have evolved. And guess what? They all share a secret superpower: activating AMPK! Join us as we uncover what makes these drugs so “wonder-ful”!
00:00 Intro
01:02 First "drugs" 3,500 years ago
02:22 Invention of aspirin
02:38 Invention of Salvarson (Arsphenamine)
03:01 World War II wonder drugs: Antibiotics, Amphetamines & Methamphetamines
04:27 21st century wonder drugs: Metformin, statins, GLP-1 Agonists (Ozempic, Wegovy, Mounjaro, etc)
05:01 How do they all work? They activate AMPK
05:12 Metabolic Engineering
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