Pediatric Grand Rounds: Harnessing Biotechnological Innovation to Improve the Outcomes of Pediatric Cancer Patients
Chuck Gawad, MD, PHD - Stanford School of Medicine
Session Description
The past two decades have seen a rapid expansion in the availability of sophisticated new technologies for making biological measurements. Some of these technologies, such as next-generation sequencing, have been integrated into routine clinical practice. In this lecture, I will discuss three new technologies being developed by my group and our collaborators. I will first discuss our use of cell-free DNA sequencing and the IBM electronic nose to diagnose and predict infections in immunocompromised patients. I will then describe our invention of a new genome amplification method, and its application to cancer research and beyond.
Education Goals
To understand the potential clinical uses of microbial cell-free DNA sequencing
To learn how point-of-care infectious diagnostics could change clinical practice
To understand how genetic heterogeneity contributes to cancer treatment resistance
To learn about the uses for single-cell sequencing in cancer research
