"Crap rolls downhill, Schmitt."
- Grey's anatomy (Season 20 Episode 08)
Grey's Anatomy is an American medical drama television series focusing on the personal and professional lives of surgical interns, residents, and attendings at the fictional Seattle Grace Hospital, later named the Grey Sloan Memorial Hospital.
The series premiered on March 27, 2005, on ABC as a mid-season replacement. The show's title is an allusion to Gray's Anatomy, a classic human anatomy textbook.
The original cast consisted of nine star-billed actors: Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers, T. R. Knight, Chandra Wilson, James Pickens Jr., Isaiah Washington, and Patrick Dempsey. For most of its run, the series revolves around Dr. Meredith Grey (Pompeo), chronicling her progression from surgical intern to fully-qualified doctor to the hospital's chief of general surgery.
The cast has undergone major changes throughout the series' run, with only three original members remaining by the 19th season - Pompeo, Wilson, and Pickens. Pompeo stepped back from the series in its 19th season, at which point the show shifted to more of an ensemble format.
Grey's Anatomy has two spin-off series: Private Practice (2007-2013) and Station 19 (2018-2024). Other shows which may parallel in plotline and medical dramatics would be programs like ER, which ran from 1994 to 2009, overlapping early seasons of Grey's Anatomy.
