Proteolysis-targeting chimera (PROTAC) compounds developed at the University of Dundee are being made available free of charge by the pharmaceutical company Boehringer Ingelheim through their scientific crowdsourcing platform opnMe.com.
PROTAC VZ185 was discovered by Vittoria Zoppi, Scott Hughes, Chiara Maniaci and Andrea Testa within the academic group of Professor Alessio Ciulli from the School of Life Sciences at the University of Dundee. The compound potently induces fast and highly selective degradation of the proteins Brd7 and Brd9 inside living cells.
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