The Avian Influenza (AI) epidemic of 2016-2017 had been the largest in Europe in more than 10 years. The circulating virus was a Highly Pathogenic (HPAI) H5N8 strain, which caused over 1,200 outbreaks in poultry farms with extremely high lethality rates, leading to massive economical losses. Italy had been heavily affected, involving 2.7 million of domestic birds in 83 infected farms.

With the aim of improving the management of the epidemic, a team of researchers at the Istituto Zooprofilattico Sperimentale delle Venezie, composed of epidemiologists and virologists, adopted a multidisciplinary approach integrating epidemiological and phylogenetic information, allowing to reliably track the disease spread among farms and to re-modulate the containment strategy almost in a real-time fashion.

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