🚨Info on COVID vaccination in 2nd trimester!
✔️Evaluated maternal and neonatal SARS-CoV-2 antibody (Ab) levels at birth after vaccination during the 2nd trimester.
➡️No subjects had prior infections, and all had 2 doses of vaccine.
✔️Ab titers were measured for 129 women and 114 neonates.
➡️All maternal and newborn SARS-CoV-2 IgG tests had + results.
➡️Neonatal titers measured approx. 2.6X higher than maternal titers, representing 100% placental antibody transfer.
✔️Maternal and neonatal Ab titers were inversely correlated with maternal age, meaning that advanced maternal age was associated with lower maternal and neonatal Ab titers.
➡️Physicians of those with advanced maternal age should be aware of the lower Ab levels.—GET BOOSTED!
✔️There was an inverse correlation of Ab titers with the time interval from the 2nd vaccination; thus, if the 2nd vaccination was performed earlier in pregnancy, both maternal and neonatal titers were found to be lower at delivery.
➡️There may be a point at which the Ab levels begin to stabilize and possibly decrease.
✔️COVID-19 vaccination during the 2nd trimester was associated with high Ab titers in the subject and with even higher levels in neonates, suggesting that earlier timing of vaccination is important for pregnancy.
✔️There may be an advantage of early vaccination during pregnancy rather than during the 3rd trimester.
✔️Later vaccination may be associated with increased risk of a pregnancy complicated by COVID-19, which has been shown to be associated with a higher risk for hazardous pregnancy outcomes, as well as less time for efficient transfers of Abs to fetus.
DON’T WAIT TO GET VACCINATED OR BOOSTED!
#getvaccinated #getboosted #teamhalo #covidvaccine #pregnancy #shorts
