This summarizes findings from several studies investigating the tissue-specific roles of the Glucagon-Like Peptide-1 Receptor (GLP-1R) using Cre-Lox technology in mice. The studies explore the GLP-1R's function in various tissues, including the central nervous system (CNS), cardiomyocytes (heart muscle cells), and pancreatic beta cells, providing insights into its diverse roles in metabolism, appetite, and cardiovascular function.
