Nicole Vignola's Rewire uses neuroscience to explain how to change negative thought patterns and behaviors. The book presents neuroplasticity—the brain's ability to adapt—as the key to personal transformation. Vignola offers a "neuro toolkit" of practical techniques, including meditation, visualization, and managing stress and anxiety, to help readers rewire their brains for lasting positive change. She emphasizes the importance of recognizing negative biases, breaking self-limiting beliefs, and cultivating gratitude. The text also discusses overcoming grief and loss, building self-trust, and managing conditions such as ADHD.

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