This webinar is on the tools in MolSoft's ICM-Pro Desktop Modeling software for incorporating induced fit into ligand docking and screening. There is more information at www.molsoft.com

2:00 Introduction to induced fit methods in ICM
4:00 Multiple Receptor Docking (4D)
30:30 Hybrid Docking - Flexible Side Chains, Hydroxyls Waters..
46:00 SCARE method - Scan Alanines and Refine - open up a pocket and model flexibility
49:00 Modeling methods to build an ensemble of structures

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