Some points to remember :
The goal of the catheter-based approach is to restore blood, as quickly as possible, to the threatened limb, with the use of drugs, mechanical devices, or both, using several options for reperfusion: endovascular procedures such as percutaneous catheter-directed thrombolysis (CDT), percutaneous thromboaspiration (PAT), with or without thrombolytic therapy, or percutaneous mechanical thrombectomy (PMT).

Absolute Contraindications to catheter-directed thrombolysis
Active bleeding
Intracranial hemorrhage
Presence or development of compartment syndrome
Severe limb ischemia, requiring immediate operative intervention
For streptokinase: prior administration of streptokinase

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