#boneresorptionbyosteoclasts#effectofparathyroidhormoneonbone#bonecells#medtutorials


Bone resorption by osteoclasts. Parathyroid hormone (PTH) binds to receptors on osteoblasts, causing them  to form receptor activator for nuclear factor κ-B ligand  (RANKL) and to release macrophage-colony stimulating factor (M-CSF).RANKL binds to RANK and M-CSF binds to its receptors on preosteoclast cells, causing them to  differentiate into mature osteoclasts. 


#boneresorptionbyosteoclasts#effectofparathyroidhormoneonbone#bonecells#medtutorials

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