Shane Parrish sits down with the renowned biochemist Dr. Rhonda Patrick to explore the intricate world of nutrition and health. Dr. Patrick provides a deep dive into the role micronutrients play in our daily health, detailing how deficiencies and insufficiencies in vitamins, minerals, fatty acids, and amino acids can lead to serious health issues over time. Shane and Dr. Patrick also discuss the science behind deliberate heat exposure. She outlines the optimal sauna conditions—temperature, duration, and frequency—necessary for these health benefits and explains how the physiological mechanisms work.

Rhonda Patrick has a Ph.D. in biomedical science and a Bachelor of Science degree in biochemistry/chemistry from the University of California, San Diego. She has done extensive research on aging, cancer, and nutrition.


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00:00 - Intro
01:22 - A philosophy for nutrition
12:18 - Micronutrients through supplements vs. food
22:25 - Wild-caught vs. farm-raised fish
25:26 - Organic vs. non-organic vegetables
32:56 - On macronutrients
37:02 - How protein levels differ in different foods
42:09 - The best morning smoothie recipe
51:30 - Dr. Patrick grades Shane's "GOAT" smoothie recipe
55:56 - Grass-fed vs. non-grass fed
01:01:22 - On vitamin D (Is sunscreen killing us more than the sun?)
01:16:30 - Deliberate heat and cold exposure
01:41:09 - Top three behavioral and diet interventions for life and health improvements

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Like the mentor you’ve always dreamed of having, The Knowledge Project shares timely yet timeless lessons for work and life. Past guests include Naval Ravikant, Daniel Kahneman, Jim Collins, Angela Duckworth, Seth Godin, Melanie Mitchell, & Esther Perel.

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