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Derek is a fitness educator & the entrepreneur behind More Plates More Dates & an expert in molecules commonly used & misused by bodybuilders & athletes. This conversation explores various compounds like growth hormone, testosterone, androgens, SARMs, estrogen, finasteride, peptides, & much more. Derek walks through how these molecules are used by athletes to gain an edge while also exploring their impact on disease risk, hair loss, fertility, & more. This conversation aims to provide insights into whether these compounds are uniformly harmful or if there are broader implications that could benefit the general population.
We discuss:
0:00:00-Intro
0:00:47-Derek’s experimentation with anabolic steroids at a young age
0:10:28-Acquiring steroids from underground labs & the potential long-term fertility concerns early in his bodybuilding career
0:15:56-Backstory on More Plates, More Dates & Derek’s unique ability to blend scientific knowledge with personal observation
0:21:23-Growth hormone—from extreme use-cases to the more typical—& the misconception that it’s the “elixir of life”
0:29:34-Growth hormone 101: definition, where it comes from, & the challenges of measuring it
0:41:43-Does exogenous growth hormone compromise one’s ability to make endogenous growth hormone?
0:43:51-Use of growth hormone in restoration of tissue during periods of healing
0:51:45-Growth hormone-releasing peptides to increase endogenous GH: various peptides, risks, benefits & comparison to exogenous growth hormone
1:07:12-Role of growth hormone in building muscle & burning fat, as well as its effects on sleep & daytime lethargy
1:15:00-Evolution of drug use in the sport of bodybuilding
1:27:01-What explains the protruding abdomens on some bodybuilders & athletes?
1:33:20-Death of bodybuilders
1:42:15-Complex interplay of hormones, & the conversion of testosterone into metabolites like DHT & estrogen
1:52:23-Post-finasteride syndrome & how Derek successfully treated his hair loss
2:07:55-Testosterone replacement therapy: compelling use-cases, side effects, & optimal dosing schedules
2:28:56-Aromatase inhibitors to suppress estrogen, & the misconceptions around estrogen in men
2:34:38-Other hormones beyond testosterone for male sex hormone replacement
2:38:45-History of anabolic compounds, & the differing effects of various anabolic testosterone derivatives & related drugs
2:44:24-Use of SARMs by bodybuilders
2:51:53-Anabolic steroid & testosterone regimens of professional bodybuilders & the downstream consequences
3:01:20-Challenge of accurate hormone testing in the presence of anabolic steroids & supplements
3:04:10-Use of Clomid, hCG, & enclomiphene
3:18:37-Concerns about fertility: comparing the use of testosterone & hCG
3:31:33-Use of BPC-157 peptide for healing injuries
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About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, & all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, & much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan & simultaneously improving their healthspan.
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Disclaimer: This podcast is for general informational purposes only & does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information & the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, & they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures & the companies I invest in or advise, please visit my website where I keep an up-to-date & active list of such companies. For a full list of our registered & unregistered trademarks, trade names, & service marks, please review our Terms of Use: [ Ссылка ]
