Deepti Radia, MBBS, BSc, MRCPI, FRCPath, MSc Med Ed, Guy's and St Thomas' NHS Foundation Trust, London, UK, presents the updated analyses of the PATHFINDER study (NCT03580655) investigating avapritinib, a highly selective KIT D816V inhibitor, in patients with advanced systemic mastocytosis (AdvSM). The responses to treatment have been encouraging, particularly in treatment-naive patients, with significant decreases in mast cell disease burden and improvement in blood counts. This interview took place at the 64th Annual Scientific Meeting of the British Society for Haematology (BSH) Congress in Liverpool, UK.

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