Primary orthostatic tremor is a rare, progressive movement disorder that causes unsteadiness when standing still, due to a rapid tremor affecting the legs and trunk. The tremor is sometimes described as having 'shaky legs,' and it improves or disappears when walking, sitting, or lying down.
Primary orthostatic tremor is a rare neurologic movement disorder characterized by unsteadiness in gait and (more pronouncedly) in stance due to a pathognomonic 13–18 Hz tremor that can be detected by surface EMG of both legs while standing. Involvement of the upper extremities is less frequent but has also been described. The pathophysiology of POT remains poorly understood, and limited treatment options are available. To date, multiple therapeutic approaches, of which gabapentin, benzodiazepines, primidone, propanolol, pregabalin and phenobarbital have been shown to be likely or possibly beneficial, have been tried
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