Dr. Sandesh Gupta's treatment for acanthosis nigricans, which commonly causes darkening of the neck and underarms, involves a multi-faceted approach. The primary goal is to address any underlying conditions such as obesity, insulin resistance, or hormonal disorders like polycystic ovary syndrome (PCOS). Effective management includes lifestyle changes such as a healthy diet and increased physical activity to reduce insulin resistance.
For topical treatment, options like retinoids, vitamin D analogs, and alpha hydroxy acids may be prescribed to help lighten the affected skin. In more severe cases, procedures like laser therapy can be considered. Additionally, metformin and other insulin-sensitizing medications are often used to control insulin levels, thereby reducing skin thickening.
Patient education is crucial, emphasizing the importance of controlling blood sugar levels and weight management. It's also advised to avoid medications that might exacerbate the condition, such as certain hormonal treatments. Regular follow-ups with a healthcare provider are necessary to monitor progress and adjust treatment as needed.
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