A plume of smoke rose above central Paris on Wednesday after witnesses reported hearing a large explosion.
Four people were left in critical condition after the blast, police said, with at least 20 more injured. Two people are reportedly missing according to French news agency AFP.
Paris police chief Laurent Nunez said the "fire is under control" but had not yet been extinguished at the time of the statement.
Witnesses and local reporters said that they had seen the facade of a building collapse in the French capital's 5th arrondissement, also known as the Latin Quarter.
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