Surgery is the standard of care for rectal cancer, and radiotherapy is typically given in advanced rectal cancer. Arthur Myint, MBBS, FRRP, FFRCS, FRCR, FICS, The Clatterbridge Cancer Centre, Cambridge, UK, provides an overview of novel strategies that minimize the use of surgery. Previous research has determined that approximately half of patients receiving external beam radiotherapy (EBRT) alone will progress. Findings from the Phase III OPERA trial (NCT02505750) demonstrated that additional contact radiotherapy enhances organ preservation rates. This interview took place at the American Society of Clinical Oncology (ASCO) 2023 Gastrointestinal Cancers (GI) Symposium in San Francisco, CA.

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