What information do we need to give patients who are prescribed 5-Fluorouracil? What are the potential problems that our canine friends can develop when exposed to this cream?

Here are a few references that may be helpful.

1. A dog’s life: an unfamiliar and lethal side effect of topical 5-fluorouracil. Clinical Exp Dermatology 2018;43:732.

2. Toxic Effects of Fluorouracil Cream Ingestion on Dogs and Cats. Arch Dermatology 2010;146:1195-6.

3. 5-Fluorouracil Toxicosis in the Dog. Journal of Veterinary Internal Medicine 1990;4:254-7.



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