|Routesofdrugadministration| Oral| pharmacology| Intraperitoneal| Intramuscular| Intravenous| Subcutaneous| GPAT| Experiment| Practical| Screening| Intragastric| Retroorbital| Intradermal| Subplantar| Administration of drugs to laboratory animals can be done by various routes. A key factor determining the route selected is whether the agent is being administered for local or systemic either enteral or parenteral effect. Parenteral administration methods typically produce the highest bioavailability of substances. Preparation of site for drug administration is important along with the concentration of drugs pH of the solutions to be administered and the volume of administration is important. The size of the needles and frequency of administration is also important. This video explains in a different route of administration in rats or mice with pictorial representations easy to understand and overview of needle size and optimal volumes to be administered.
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Different Routes of Drug administration in Rats/Mice
Теги
drug administrationroutespharmacologyratsmicepracticalscreeninigexperimentdrugintraperitonealintragastricoralgavagesubplantarintradermalintravenousretroorbitalsubcutaneousneedle sizesyringeenteralparenteralintranasaltopicalinhalationrectalsolutionconcentrationbody weightvehiclestandardcreamointmenteye dropsspraygelinjectionperitonealper oralintracardiacsuspensioninterscapularthighplexustransdermalintracerebral