This lecture was a historical walk down the use of serotonergic psychedelics, from the earliest recorded evidence of 6000 years ago, to their listing as scheduled drugs of abuse and to the recent revival of interest in their potent behavioral effects. Vidita Vaidya describes the experimental evidence in animal models that highlight the ability of these agents to potently modulate mood behavior.

This talk also discussed the neurocircuits and molecular pathways targeted by these fascinating compounds, speculating on future breakthrough therapies for mood dysfunction.

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