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Stress-induced Antibiotic Susceptibility Testing on a Chip - a 2 minute Preview of the Experimental Protocol
Maxim Kalashnikov, Jennifer Campbell, Jean C. Lee, Andre Sharon, Alexis F. Sauer-Budge
Fraunhofer USA Center for Manufacturing Innovation,; Harvard Medical School, Division of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital; Boston University, Department of Mechanical Engineering; Boston University, Department of Biomedical Engineering;
We have developed a microfluidic platform for rapid antibiotic susceptibility testing. Fluid is passed at high speeds over bacteria immobilized on the bottom of a microfluidic channel. In the presence of stress and antibiotic, susceptible strains of bacteria die rapidly. However, resistant bacteria can survive these stressful conditions.
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