This video reviews potency vs efficacy, and details a way to learn potency and efficacy of medications.
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The video explores the concept of potency in pharmacodynamics, details potency vs efficacy, focusing particularly on first-generation antipsychotics. To learn potency, you have to know potency refers to the amount of drug needed to produce a specific effect, with higher potency indicating a lower concentration required for the effect. The potency and efficacy of medications differ, as efficacy refers to the maximum effect a drug can produce. The video illustrates potency using the example of two drugs, both full agonists, administered at their half maximal effective concentration. Despite having equal efficacy, the drug with higher potency achieves its effect at a lower dose, as depicted in a dose-response curve. The video emphasizes that potency does not imply effectiveness; it simply signifies the concentration needed for an effect. It further distinguishes potency from efficacy by introducing a high potency partial agonist, which achieves its effect at a lower dose compared to a drug with higher efficacy but lower potency. Ultimately, the video clarifies that potency and efficacy are separate measures in pharmacology, with potency reflecting the dosage required for an effect, while efficacy denotes the maximum effect achievable by a drug.

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#psychopharmacology #psychiatry #pharmacology

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