Medical oncologist Mark Scholz, MD answers YouTube commenter's questions. This episode focuses on testosterone inactivating pharmaceuticals (also known as hormone therapy, hormone blockade, or androgen deprivation), but also includes questions on active surveillance and Avodart, F-18 scans, and unorthodox approaches to treating unfavorable high-risk disease in younger men.

0:11 Dr. Scholz talks about the Axumin F-18 test then later mentions F-18 bone scans. Is this the same test or two different ones?

1:37 I have a 70cc prostate and a PSA of 7.0. I'm currently on active surveillance for Gleason 3+3 cancer. I started taking Avodart and Flomax for BPH and was told that while on Avodart, I need to double my PSA to get an accurate reading. My PSA has remained at 7.0 for over a year. Should I assume that my actual PSA is around 14.0? Is this a cause for concern?

3:16 What happens when you have a Gleason 6 and a really high PSA?

4:21 Which treatment is better for advanced prostate cancer (T4 stage) for a 54-year-old man as a first-line treatment in addition to standard first-generation hormone therapy (e.g. Lupron)? Enzalutamide (trade name Xtandi) or docetaxel (Taxotere) chemotherapy?

6:12 How concerned should I be about the effects of short-course TIP?

7:00 What can I do about mood swings from TIP? Is there anything a partner can do to help?

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