After you sort out the early food and O2 you end up needing steel, ceramic and plastic. This all requires a cooling solution as well which requires steel and plastic. How do you get the required materials without having the materials you need to get them. The answer, dupes a bunch of heat into another biome.

This save had 1200kg steel and 200kg plastic so you can practice setting up your own industrial brick.
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This save has the cooling loop settings, don't put the temp lower than -3 or you might freeze the water in the pipes (There is some wiggle room if you want to experiment, aquatuner reduces the temp by -14 and polluted water freezes at about -20 so theoretically you could get set as low as -6)
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