Webinar Originally Aired: 20 February 2019
Presenter: Dr. Maciej Czerwinski, XenoTech Director of Consulting

Synopsis:
On October 15th, 2018, XenoTech presented on "In Vitro Direct and Cytokine-Mediated Effects of Therapeutic Peptides and other Biologics on CYP Enzymes" at the Peptide ADME Discussion Group Workshop in Gothenburg, Sweden. Following subsequent requests for a follow-up webinar, Dr. Czerwinski will be presenting on the following subjects...

Key concepts discussed in this webinar will include:
- Immunomodulators
- Mechanisms of immunomodulator drug-drug interactions (DDI)
- Regulatory guidance on evaluating DDI potential of biologics
- Study design to evaluate direct and cytokine-mediated effects of immunomodulators on drug metabolizing enzymes
- Case studies of experiments conducted according to our study design...

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More information on our biologic-small molecule DDI services: [ Ссылка ]
Other previously aired webinars:
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Upcoming webinars:
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About the presenter: Maciej Czerwinski currently serves as Director of Consulting at XenoTech. Maciej received his PhD from the University of Maryland at Baltimore Medical School in the Department of Pathology. He conducted his doctoral thesis research in the Laboratory of Dr. Frank Gonzalez at National Cancer Institute in Bethesda, followed by a post-doc at the Department of Pharmaceutics, University of Washington in Seattle. He has been with XenoTech since 1999 and guides the development of products and services for the in vitro analysis of drug safety. Maciej designed a patented method to analyze the in vitro cytokine-mediated drug-drug interactions between biologics and small molecule drugs. Dr. Czerwinski is also the inventor of XenoTech’s CryostaX single-freeze pooled hepatocytes.

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