Kinetically monitor and quantify single spheroid invasions using the Incucyte®️ Single Spheroid Invasion Assay.

Watch this video of U87-MG spheroids embedded in Matrigel®️ showing the extensive invasive phenotype of cells. Data was generated using the Incucyte®️ Spheroid Analysis Software Module.

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Why study solid tumor invasion?
Cell invasion is considered to be a hallmark of malignant cancers and plays a key role in metastasis. The invasive and metastatic potential of cancer cells is highly responsible for cancer patient mortality.

The ability of tumor cells to form a metastatic tumor is primarily determined by the cell’s ability to change and reorganize its cellular morphology and to degrade the extracellular matrix (ECM). Understanding the mechanisms concerned in tumor cell invasion may lead to limiting tumor progression and, as a result, to a reduction in mortality for many cancer patients.

With the Incucyte® Single Spheroid Invasion Assay, you can now accurately study invasive potential of tumor spheroids overtime – inside your incubator.

Gain deeper insight into the invasion, progression and response to treatments of tumor spheroids using our lab-tested protocol and integrated, label-free analysis and answer questions faster.

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