From @acog:
Oxytocin is one of the most commonly used drugs in the United States. The physiology of oxytocin-stimulated labor is similar to that of spontaneous labor, although individual patients vary in sensitivity and response to oxytocin. Based on pharmacokinetic studies of synthetic oxytocin, uterine response ensues after 3–5 minutes of infusion, and a steady level of oxytocin in plasma is achieved by 40 minutes 23. The uterine response to oxytocin depends on the duration of the pregnancy; there is a gradual increase in response from 20 to 30 weeks of gestation, followed by a plateau from 34 weeks of gestation until term, when sensitivity increases. Lower body mass index and greater cervical dilation, parity, or gestational age are predictors of successful response to oxytocin for induction.
#pregnancy #pregnant #birth #childbirth #laboranddelivery #pitocin #oxytocin #blackboxwarning #induction #inductionoflabor #electiveinduction
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