Professor Karikó is an adjunct professor at the University of Pennsylvania, where she worked for 24 years before joining BioNTech SE in 2013 as a senior VP. She is also a professor at the University of Szeged, Hungary from where she received her Ph.D. in biochemistry in 1982. For decades, her research has been focusing on RNA-mediated mechanisms with the ultimate goal of developing mRNA for protein therapy. She investigated RNA-mediated immune activation and together with Drew Weissman discovered that nucleoside modifications suppress the immunogenicity of RNA, which widened the therapeutic potentials of mRNA. Her patent, co-invented with Drew Weissman, was used to create the FDA-approved covid-19 mRNA vaccines by BioNTech/Pfizer and Moderna.

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