Sattva S Neelapu, MD, The University of Texas MD Anderson Cancer Center, Houston, TX, outlines updates in CAR T-cell therapies in lymphoma. Specifically discussed is the CAR-T construct, axicabtagene ciloleucel, which is approved for the treatment of relapsed/refractory large B-cell lymphoma on the basis of the ZUMA-1 trial (NCT02348216), as well as the outcomes of the JULIET (NCT02445248) & TRANSCEND (NCT02631044) studies. This interview was recorded via an online conference call with The Video Journal of Hematological Oncology (VJHemOnc).
An update of CAR T-cell therapies in lymphoma
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Speaker: Sattva NeelapuInstitution: The University of Texas MD Anderson Cancer CenterEvent: VJVirtualEvent: SOHO 2020Format: InterviewSubject: LymphomaSubject: Non-Hodgkin LymphomaField: CAR-T & Cellular TherapyMedicines: Axicabtagene CiloleucelField: Trial UpdatesField: TreatmentTrial: ZUMA-1NCT02348216Medicines: Lisocabtagene MaraleucelTrial: ZUMA-2Medicines: Brexucabtagene AutoleucelTrial: JULIETTrial: TRANSCEND-NHL-001Trial: ZUMA-5