Alprostadil Tablet Uses In Urdu/Hindi | Penil Injection for Erectile Dysfunction | Alprostadil Cream


Alprostadil is a medication primarily used to treat erectile dysfunction (ED) and certain other conditions related to blood flow. Here's an overview of its uses, side effects, and contraindications:
Uses:
1. Erectile Dysfunction (ED):- Alprostadil works by relaxing smooth muscle and widening blood vessels in the penis, which enhances blood flow and facilitates an erection. It's available in different forms:
• Intracavernosal Injection: Administered directly into the penis.
• Intraurethral Suppository:- Placed into the urethra.
• Topical Cream: Applied externally on the penis.
2. Patent Ductus Arteriosus (PDA) Closure:- Alprostadil can be used to keep the ductus arteriosus open in infants with certain congenital heart defects until surgery can be performed.
3. Peripheral Arterial Disease (PAD): -It's sometimes used to improve blood flow in certain conditions affecting the arteries, like PAD.


Side Effects:-
1. Injection Site Reactions: Pain, bruising, or bleeding at the site of injection.
2. Penile Pain:- Especially common with intracavernosal injections.
3. Priapism:- A prolonged and painful erection lasting more than four hours. It's a medical emergency and requires immediate attention to prevent tissue damage.
4. Hematoma:- Collection of blood outside blood vessels.
5. Dizziness or Lightheadedness:- Especially if the medication leads to a sudden drop in blood pressure.
6. Flushing or Redness:- Especially with intracavernosal injections.
7. Hypotension:- Low blood pressure, especially if the medication is absorbed systemically.

Contraindications:-
1. Allergy:-
Individuals allergic to alprostadil or similar medications should avoid it.
2. Conditions Predisposing to Priapism:-
Such as sickle cell anemia, multiple myeloma, or leukemia.

3. Penile Implants: -
If a person has a penile implant, they shouldn't use alprostadil injections.
4. Bleeding Disorders:-
Alprostadil can increase the risk of bleeding, so it should be used cautiously in individuals with bleeding disorders or those taking blood-thinning medications.
5. Cardiovascular Disease:-
Use with caution in individuals with heart disease, as alprostadil can affect blood pressure.
6. Anatomical Deformities of the Penis:-
Certain structural abnormalities of the penis may increase the risk of complications with alprostadil use.
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