Universal Vaccine is an ideal way to prevent future pandemics and is in great demand to control the current ever-evolving pathogen causing a lasting pandemic. Both preventive and therapeutic vaccines are very hard to develop using traditional methods, and universal vaccines are even harder. However, we can leverage AI and integrate protein science in universal protein vaccine design to expedite the process, possibly from years to months.

Our AI can generate antigen sequences by learning all past infectious pathogen proteomes and compute up to 10^10-25 times antigen-antibody interactions within several days to identify the common immunogenicity. The common immunogen can be computed based on respective cross-binding capability with known human plasma antibodies for B-cell immunogenicity assessment; T-cell immunogenicity will be accessed by computing the numerated computer-generated antigens against all MHC binding. By high-throughput production, screening and validation, ideal candidates for universal vaccine study can be realized and selected out.

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