All you need to know about bone marrow disorder
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We'll be talking about these items in this video:
- What is bone marrow disorder?
- How to diagnose bone marrow disorder?
- What is the CBC test?
- What are bone marrow disorders?
- What are the bone disorders?
- What causes bone marrow infections?
- How many types of bone marrow disorders are there?
- What are the bone marrow disorder types?
- What are the most common bone marrow disorders?
- How to treat bone marrow disorder?
- What are the bone marrow disorders' side effects?
- How to avoid bone marrow disorder?
- What are the bone marrow disorder effects on the body?
- What is bone marrow disease?
What are bone marrow disorders?
Several diseases or conditions can affect the structure and function of the bone marrow, which are called bone marrow disorders. This, in turn, can affect the production or function of any blood cells or their immature precursors. Disorders of the bone marrow and blood cells that result from it can be very minor and cause mild or nonspecific symptoms over a long period of time, or they can be severe and life-threatening. Some chronic diseases can only be diagnosed at annual checkups when a complete blood count (CBC) is done as a general health check.
Some of the most common bone marrow disorders are:
Bone marrow cannot produce one or more cell types (e.g., aplastic anemia). Adequate amounts of nutrients such as iron, vitamin B12, or folate affect the bone marrow's ability to produce normal red blood cells. The ones that are made may be small (microcytic), large (macrocytic), or the amount of hemoglobin in them may be low (pale).
White blood cells such as abnormal lymphocytes or plasma cells are overproduced (e.g., lymphomas, multiple myelomas).
Bone marrow infections can be caused by viruses, bacteria, or fungi and affect cell production. One or more cell types may begin to produce more.
Bone marrow produces abnormal cells that do not mature and do not work correctly (for example, leukemias, myelodysplastic syndrome).
Another bone marrow disorder is that the network of supporting fibrous tissue in the bone marrow increases and compresses the cells inside the brain, resulting in abnormally shaped cells and small cells (e.g., myelofibrosis).
Cancer may spread from other parts of the body (metastasis) to the bone marrow and affect cell production.
Types of bone marrow disorders
The following is a list of some of the conditions and diseases that can affect the structure and function of the bone marrow and cause bone marrow disorders.
Leukemia: it is called white blood cell cancer, which can affect any of the five types of WBCs and is a type of bone marrow disorder. It occurs suddenly (acute) or over a longer period of time (chronic). It may involve myeloid cells (neutrophils, monocytes, eosinophils, basophils, and their precursors) or lymphocytes. It starts with an abnormal cell that continues to clone continuously. The resulting leukemia cells do not function normally. They do not fight infections, producing normal WBCs, and red blood cells (RBCs and platelets). People with leukemia may have recurrent infections, fatigue, bleeding, bruising, anemia, night sweats, and bone and joint pain. Spleen, which filters the blood and removes old cells, may enlarge, as may this species' liver and lymph nodes.
This can be accompanied by an increase or decrease in the number of other blood cells, which may become inhibited. This leads to symptoms associated with blood cell overproduction, deficiencies, and dysfunction in the body.
Myelodysplastic Syndromes (MDS): A group of diseases caused by abnormal production of bone marrow cells and is a type of bone marrow disorder. Often with MDS, the brain appears to produce many blood cells. Still, they are defective and die before they can be released into the bloodstream (dysfunctionally). This can lead to symptoms of anemia, infection, or excessive bleeding and bruising.
Anemia: Low neutrophil counts (neutropenia) or thrombocytopenia that do not respond to treatment (reflex) sometimes require one person to receive blood.
Dysplasia: The appearance of an abnormal cell (dysplasia) in one or more cell lines. Increased immature precursors (blasts) in the brain, with risk of acute myeloid leukemia
Plasma cell disorders:
such as multiple myeloma are conditions that are accompanied by the overproduction of a single clone of fully mature B cells (lateral differentiation) called plasma cells. The primary function of plasma cells is to produce the protein-targeted immunoglobulin antibody, which helps protect the body against infections.
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Bone Marrow Diseases - What You Need To Know
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