The goal of this study was to understand the components in particles responsible for reactive oxygen species (ROS) formation under physiological conditions. The investigators conducted a field campaigns in the South Coast Air Basin, aimed at capturing photochemical smog; and in Fresno, which has significant contributions from biomass burning. Samples were extracted in simulated lung fluid, and analyzed for their ability to generate ROS such as hydrogen peroxide (H₂O₂) and hydroxyl radical (.OH) and to consume dithiothreitol (DTT) The contributions of transition metals and quinones to ROS formation was also investigated.
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