Musculoskeletal simulations of movement are traditionally performed using rigid multibody models with simplified joint representations that do not account for the deformability and complex motion of biological tissues and articulations. However, several pathological conditions and treatments, such as osteoarthritis and total joint replacement, can be best investigated within a deformable modeling framework, such as that based upon finite element methods.
In this webinar, Kevin Shelburne, Alessandro Navacchia, and Azhar Ali from the University of Denver present a conceptual overview of multi-scale musculoskeletal modeling, linking these two simulation frameworks together. Using two examples, they show how the outputs from a multibody OpenSim musculoskeletal simulation can be used with joint-level deformable finite element models.
Visit [ Ссылка ] to find models mentioned in the webinar and to continue the discussion from the webinar Q&A session.
Read more about this work:
-A Navacchia, V Kefala, KB Shelburne (2016) “Dependence of muscle moment arms on in-vivo three-dimensional kinematics of the knee,” Annals of Biomedical Engineering (in press). ([ Ссылка ])
-AA Ali, S Shalhoub, AJ Cyr, CK Fitzpatrick, LP Maletsky, PJ Rullkoetter, KB Shelburne (2016) “Validation of predicted patellofemoral mechanics in a finite element model of the healthy and cruciate-deficient knee,”Journal of Biomechanics, 49(2):302-9. ([ Ссылка ])
-A Navacchia, CA Myers, PJ Rullkoetter, KB Shelburne (2016) “Prediction of in vivo knee joint loads using a global probabilistic analysis,” ASME Journal of Biomechanical Engineering, 138(3):4032379. ([ Ссылка ])
-MD Harris, AJ Cyr, AA Ali, CK Fitzpatrick, PJ Rullkoetter, LP Maletsky, KB Shelburne (2016) “A Combined Experimental and Computational Approach to Subject-Specific Analysis of Knee Joint Laxity,” ASME Journal of Biomechanical Engineering (in press). ([ Ссылка ])
-A Navacchia, PJ Rullkoetter, P Schutz, R List, CK Fitzpatrick, KB Shelburne (2016) “Subject-specific multiscale modeling of muscle force and knee contact in total knee arthroplasty,” Journal of Orthopaedic Research, 34(9):1576-87. ([ Ссылка ])
-Gaffney BM, Harris MD, Davidson BS, Stevens-Lapsley JE, Christiansen CL, Shelburne KB (2015) “Multi-joint compensatory effects of unilateral total knee arthroplasty during high-demand tasks,” Annals of Biomedical Engineering, 44(8):2529-41. ([ Ссылка ])
-JC Ivester, AJ Cyr, MD Harris, MJ Kulis, PJ Rullkoetter, KB Shelburne (2015) “A Reconfigurable High-Speed Stereo-Radiography System for Sub-millimeter Measurement of In-vivo Joint Kinematics,” ASME Journal of Medical Devices, 9(4): 041009. ([ Ссылка ])
