Videos mentioned:
DHT trash hormone part 2: [ Ссылка ]
Dark side of finasteride: [ Ссылка ]

Sources:
1. Loss of 5α-reductase type 1 accelerates the development of hepatic steatosis but protects against hepatocellular carcinoma in male mice - PubMed. Accessed October 17, 2022. [ Ссылка ]
2. Marked Suppression of Dihydrotestosterone in Men with Benign Prostatic Hyperplasia by Dutasteride, a Dual 5α-Reductase Inhibitor | The Journal of Clinical Endocrinology & Metabolism | Oxford Academic. Accessed October 19, 2022. [ Ссылка ]
3. Westerbacka J, Yki-Järvinen H, Vehkavaara S, et al. Body fat distribution and cortisol metabolism in healthy men: enhanced 5beta-reductase and lower cortisol/cortisone metabolite ratios in men with fatty liver. J Clin Endocrinol Metab. 2003;88(10):4924-4931. doi:10.1210/jc.2003-030596
4. Upreti R, Hughes KA, Livingstone DEW, et al. 5α-reductase type 1 modulates insulin sensitivity in men. J Clin Endocrinol Metab. 2014;99(8):E1397-1406. doi:10.1210/jc.2014-1395
5. Livingstone DEW, Barat P, Di Rollo EM, et al. 5α-Reductase type 1 deficiency or inhibition predisposes to insulin resistance, hepatic steatosis, and liver fibrosis in rodents. Diabetes. 2015;64(2):447-458. doi:10.2337/db14-0249
6. Hazlehurst JM, Oprescu AI, Nikolaou N, et al. Dual-5α-Reductase Inhibition Promotes Hepatic Lipid Accumulation in Man. J Clin Endocrinol Metab. 2016;101(1):103-113. doi:10.1210/jc.2015-2928
7. Finasteride. National Institute of Diabetes and Digestive and Kidney Diseases; 2018. Accessed October 17, 2022. [ Ссылка ]
8. Traish AM. Health Risks Associated with Long-Term Finasteride and Dutasteride Use: It’s Time to Sound the Alarm. World J Mens Health. 2020;38(3):323-337. doi:10.5534/wjmh.200012

свернуть